SS-31

SS-31 Hilma Biocare 10 mg

SS-31, also known as elamipretide or MTP-131, is a synthetic tetrapeptide that targets mitochondria. Its binding to cardiolipin, a phospholipid primarily found in the inner mitochondrial membrane, is central to its mechanism of action.

Product features

Action on the mitochondrial membrane

This small, positively charged peptide concentrates in the mitochondria. The mechanisms studied mainly concern their function and integrity:

• Cardiolipin: stabilization of this phospholipid and of the organization of the respiratory chain complexes.
• Oxidative stress: modulation of cytochrome c function and limitation of electron leakage associated with the formation of reactive oxygen species.
• ATP production: studied improvement of the coupling of oxidative phosphorylation and the response to ADP in aging or stressed mitochondria.
• Membrane integrity: protection studied against the opening of the permeability transition pore under stress conditions.

Research areas

• Cellular energy: ATP production capacity, redox balance and functional quality of mitochondria.
• Exercise tolerance: studies in mitochondrial myopathies and assessment of physical capacity. These results do not demonstrate a performance gain in healthy athletes.
• Cardiovascular function: research on myocardial energetics, ischemia and mitochondrial dysfunctions associated with certain cardiac conditions.
• Nervous system, kidneys and metabolism: exploring cellular protection in different models of stress and mitochondrial dysfunction.

Quantities described

The recommended dosage ranges for this product are 1 to 2 mg per day for mitochondrial support, and 4 to 10 mg per day in regimens described as intensive. These are not validated dosages for prevention, sports recovery, or for this Hilma Biocare preparation.

Associations mentioned

• MOTS-c: association presented to jointly explore mitochondrial function and AMPK-related metabolic signaling pathways.
• BPC-157: association mentioned when the objectives also include soft tissues or the digestive system.
• Duration and monitoring: the described uses cover defined periods of several weeks, with an evaluation of individual response. The synergy and safety of these associations remain to be established.

Preparation and storage

Each Hilma Biocare vial contains 10 mg of lyophilized powder. The presentation and labeling allow for identification of the compound and the total quantity; the final concentration depends on the volume of diluent.

• Reconstitution: the preparation described uses bacteriostatic water before subcutaneous administration.
• Unreconstituted bottle: store in a cool, dry place, away from direct light.
• After reconstitution: follow the refrigeration instructions and the shelf life specific to the product.

Health and usage information

This page provides educational product information to help you make informed choices. It is not a substitute for medical advice. If you have a health condition or questions about dosage, consult a sports medicine physician or other healthcare professional.