Semaglutide

Semaglutide 2 mg

Semaglutide is a GLP-1 receptor agonist. It acts on satiety mechanisms and blood glucose regulation. This presentation contains the active ingredient in lyophilized powder form.

Product features

Appetite and glucose regulation

• Satiety: reduction of hunger, food cravings and the amount of food needed to feel full.
• Response to glucose: stimulation of insulin secretion and reduction of glucagon secretion when blood glucose is high.
• Digestion: slowing of gastric emptying, which contributes to its action on the post-meal response.

Weight and metabolic parameters

Authorized medications containing semaglutide are used, depending on their formulation, for type 2 diabetes or weight management. For the latter indication in adults, the criteria include a BMI of at least 30 kg/m², or at least 27 kg/m² with a weight-related condition.

Weight loss is achieved through nutritional guidance and appropriate physical activity. Improvements in systolic blood pressure and lipid profile have also been observed in clinical studies. These results pertain to the formulations studied and their medical context.

Administrative guidelines

The information sheet mentions a range of 0.25 to 1 mg once a week. The dose and its gradual increase are determined by a prescription tailored to the indication, the formulation, and the patient’s tolerance.

The described route is subcutaneous, in the abdomen, thigh, or upper arm, alternating sites. Intravenous and intramuscular administrations are excluded.

The initial 8- to 12-week period mentioned in the information sheet is a descriptive guideline. The duration of treatment and follow-up objectives are determined medically.

Replenishment and concentration

The diluent, its volume, and its shelf life must be validated for this formulation. The bacteriostatic water mentioned in the datasheet should only be used if the manufacturer’s instructions specify it.

For a final volume of 1 ml containing the 2 mg from the vial, the calculated concentration is 2 mg/ml; 0.5 ml therefore contains 1 mg. These equivalencies describe a concentration, not a dose to be selected.

Observe the refrigeration conditions and shelf life of the prepared solution. The diluent has its own storage instructions.

Health and usage information

This page provides educational product information to help you make informed choices. It is not a substitute for medical advice. If you have a health condition or questions about dosage, consult a sports medicine physician or other healthcare professional.